AFA treasurer and president Brad Fox will step in as interim chief executive whilst the association looks for a replacement.
Mr Klipin, who moves to his new senior role with ANZ Wealth early next year, leaves the association after seven years in his role as chief executive.
"The decision to leave has been a very difficult one personally, however after almost seven fantastic years as chief executive, it is time to pass the baton," Mr Klipin said.
"I leave with a great sense of pride. The passion, professionalism and the culture of the AFA community is outstanding, and I know that the future is in great hands," he said.
AFA national president Michael Nowak said that Mr Fox has the experience and skill set to continue the AFA's momentum in membership growth, education delivery and bringing value to corporate partnerships.
"He has the leadership skills that will prove so vital to the profession as the Future of Financial Advice reforms are implemented," he said.
"With a new National Board in place and a strong management team, the AFA will continue to lead the profession forward into the future," he said.
